Metabolic silencing via methionine-based amino acid restriction in multiple myeloma cell lines reveals a potential new strategy for cancer therapy
Andrea Frabschka, Maximilian Friedrich Völter, Hannah Jöhren, Werner Schmitz, Charlotte Wiegand, Mohamed El‐Mesery, Corinna Koderer, Lena Wiesner, Alexander Christian Kübler, Axel Seher
This study shows that methionine restriction reduces proliferation in multiple myeloma cell lines without causing cell death, suggesting it as a potential cancer therapy.
bioRxiv · Aug 17, 2025 · PreprintCancer Biology