Activity-Dependent Alternative Splicing of Adhesion-GPCR Latrophilin-3 Controls Synapse Formation
Shuai Wang, Chelsea DeLeon, Wenfei Sun, Stephen R. Quake, Bryan L. Roth, Thomas Christian Südhof
This study shows that activity-dependent alternative splicing of Latrophilin-3 controls synapse formation through dual pathways involving GS/cAMP signaling and phase-separated protein scaffolds.
Nature · Jan 17, 2024Peer-reviewedNeuroscience