Acetyl-CoA Synthetase 1 Regulates Global Histone Propionylation and Metabolic Stress Responses
Keith C. Garcia, Chengjin Zhu, Ashby J. Morrison
The paper identifies histone propionylation as a response to glucose starvation and shows that Acs1 generates propionyl-CoA for this modification, linking metabolism to chromatin regulation.
bioRxiv · May 7, 2026 · PreprintMolecular Biology