Olivier Espéli

Dietary emulsifiers and host inflammation synergistically drive genomic evolution of Crohn disease-associated E. coli toward enhanced pathogenicity

This study shows dietary emulsifiers and host inflammation together drive genomic changes in AIEC, increasing its pathogenicity.

E. coli associated with Crohn's disease exhibit distinct strategies to colonize macrophages

The paper shows that AIEC E. coli strains use different strategies to colonize macrophages and form IBCs, with variations in detoxification, biofilm formation, and macrophage responses.

DNA topoisomerase I acts as supercoiling sensor for transcription elongation in E. coli

The paper investigates how DNA topoisomerase I senses and responds to supercoiling during transcription elongation in E. coli.

Genomic contacts reveal the control of sister chromosome decatenation in E. coli

This study investigates chromosome folding in E. coli with altered decatenation activities, revealing roles for Topo IV, Topo III, MatP, and MukB in sister chromatid organization.

Engineering E. coli for magnetic control and the spatial localization of functions

This paper engineers E. coli to be magnetically controllable and capable of spatially localizing functions through asymmetric inheritance of magnetic properties.

Redesigning chromosomes for optimized Hi-C assay provides insights on loop formation and homologs pairing during meiosis

The paper redesigns a genomic region for improved Hi-C analysis, revealing insights into homolog pairing and loop formation during meiosis.