Bidirectional transcription at the PPP2R2B gene locus in spinocerebellar ataxia type 12
Chengqian Zhou, Hans B. Liu, Fatemeh Jahanbakhsh, Leon Deng, Bin Wu, Mingyao Ying, Russell L. Margolis, Pan P. Li
This study identifies bidirectional transcription at the PPP2R2B gene locus in SCA12 and shows that expanded antisense transcripts are toxic and contribute to disease pathogenesis.
Movement Disorders · Sep 21, 2023Peer-reviewedNeuroscience