PathologyRespiratory ResearchPeer-reviewed
Nephrectomy and high-salt diet inducing pulmonary hypertension and kidney damage by increasing Ang II concentration in rats
Qian Jiang, Qifeng Yang, Chenting Zhang…·Yuqin Chen
This study develops a CKD-PH rat model through 5/6 nephrectomy and high-salt diet, showing increased Ang II and RAAS imbalance, ACE2 downregulation, and metabolic changes linked to pulmonary hypertension.
7 citations