ROBUST AND EFFICIENT ACTIVE GENETICS GENE CONVERSION IN THE RAT AND MOUSE
Chenyen Lai, Óscar Álvarez-García, Kristen Read, Donald Van Fossan, Christopher M. Conner, Xiangru Xu, Dale O. Cowley, Valentino Matteo Gantz, David R. Webb, Kurt Jarnagin
The paper identifies key parameters for efficient AG gene conversion in rats and mice by testing promoter-target site pairs and Cas9 configurations.
bioRxiv · Aug 30, 2022 · PreprintGenetics