Mesenchymal Cell-Derived Extracellular Vesicles Ameliorate Age-Related Deficits in Working Memory as well as Brain MRI and CSF in vivo Biomarkers of Neurodegeneration in Rhesus Monkeys.
Evan C. Mackie, Chia-Hsin Cheng, Maya N. Alibrio, Christine Rutledge, Hongqi Xin, Michael Chopp, Ryan McCann, Douglas L. Rosene, Qiong Yang, Ella Zeldich, Maria Medalla, Bang‐Bon Koo, Tara L. Moore
This study shows that MSC-EVs improve cognitive function and reduce neurodegeneration biomarkers in aged rhesus monkeys.
bioRxiv · Nov 14, 2024 · PreprintNeuroscience