Maria Medalla

This study evaluates three pan-inhibitory viral constructs in macaques to assess their efficacy in targeting inhibitory neurons and modulating neural activity.

This study investigates how trisomy 21 affects oligodendrocyte development and neuron-glia communication in human forebrain assembloids, finding a shift toward a pre-myelinating state and disrupted myelination.

This study examines how heat and nitrate affect symbiosis in sea anemones, finding that while nitrate can temporarily buffer thermal stress, combined stressors lead to holobiont failure.

The paper identifies muscarinic receptor subtypes in primate prefrontal and cingulate cortices, revealing regional differences in receptor expression and functional properties.

This study shows that tau propagation from entorhinal cortex to hippocampal CA1 neurons leads to sex-specific cognitive and electrophysiological impairments, driven by distinct neuroimmune responses in males and females.

This study shows that MSC-EVs improve cognitive function and reduce neurodegeneration biomarkers in aged rhesus monkeys.

The paper compares the distribution and morphology of CaBP-expressing interneurons in mouse and monkey visual and frontal cortices, finding that differences are mainly driven by CaBP expression rather than species or area.

The paper develops a 3D neuron-astrocyte coculture model to study tauopathy, showing it recapitulates pathological features and responds to HSP90 inhibitor treatment.

This paper introduces WaveMAP, a method using non-linear dimensionality reduction and graph clustering to identify cell types in premotor cortex, revealing new physiological and functional diversity.