Hedgehog signaling is non-cell autonomously activated in the cystic kidney of Arl13b mutant mice
Chia-Ling Hsieh, Stephanie Jerman, Zhaoxia Sun
This study shows that Hedgehog signaling is non-cell autonomously activated in the interstitium of cystic kidneys in Arl13b mutant mice and that inhibiting this pathway reduces cyst burden and fibrosis.
Human Molecular Genetics · Jul 29, 2022Peer-reviewedGenetics