Dephosphorylation of YES kinase-mediated co-chaperone DNAJB6b phosphorylation attenuates tau protein aggregation
Meng‐Chieh Lin, Huan-Yun Chen, Te‐Sheng Lin, Sue‐Jane Lin, Pei-Jie Lin, Chia-Yu Liao, Nei‐Li Chan, Chin‐Hsien Lin, Shu‐Chun Teng
The paper investigates how phosphorylation of DNAJB6b by YES kinase affects tau protein aggregation in Alzheimer's disease, suggesting it may contribute to disease risk and identify a potential biomarker.
bioRxiv · Nov 14, 2025 · PreprintNeuroscience