Structural basis for the peptidoglycan editing activity of YfiH
Meng-Sheng Lee, Kan‐Yen Hsieh, Chiao-I Kuo, Szu-Hui Lee, Shambhavi Garde, Manjula Reddy, Chung‐I Chang
This paper determines the crystal structures of YfiH bound to its substrate and product, revealing its role as a cytoplasmic amidase that edits peptidoglycan precursors by cleaving UDP-MurNAc-L-Ser.
mBio · Feb 15, 2022Peer-reviewedMolecular Biology