Author

Shambhavi Garde

Centre for Cellular and Molecular BiologyORCID 0000-0002-9539-8159Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genomics· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Assay:long-read sequencing· 1 Approach:statistical model· 1 Research Focus:variant calling· 1

Frequent Co-Authors

Manjula ReddyiD· 2 shared Chiao-I Kuo· 1 shared Chung‐I ChangiD· 1 shared Divya Tej SowpatiiD· 1 shared Kan‐Yen HsiehiD· 1 shared Karthik Bharadwaj TallapakaiD· 1 shared Lamuk ZaveriiD· 1 shared Meng-Sheng Lee· 1 shared

Activity by Year

2022-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersGenomics

Manjula ReddyORCID

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2 papers

Recent·Most cited

NEMO: Improved and accurate models for identification of 6mA using Nanopore sequencing

Onkar Kulkarni, Lamuk Zaveri, Reuben Jacob Mathew, Nitesh Kumar Singh, Sreenivas Ara, Shambhavi Garde, Manjula Reddy, Karthik Bharadwaj Tallapaka, Divya Tej Sowpati

The paper develops improved models for detecting 6mA using Nanopore sequencing, achieving higher accuracy than existing methods.

bioRxiv · Mar 12, 2024 · PreprintGenomics

Structural basis for the peptidoglycan editing activity of YfiH

Meng-Sheng Lee, Kan‐Yen Hsieh, Chiao-I Kuo, Szu-Hui Lee, Shambhavi Garde, Manjula Reddy, Chung‐I Chang

This paper determines the crystal structures of YfiH bound to its substrate and product, revealing its role as a cytoplasmic amidase that edits peptidoglycan precursors by cleaving UDP-MurNAc-L-Ser.

mBio · Feb 15, 2022Peer-reviewedMolecular Biology