EZH2 inhibition results in genome-wide PRC2 redistribution
Chih-Chi Yuan, Ah‐Jung Jeon, Greg Tucker‐Kellogg, Barbara M. Bryant, Patrick Trojer
This study shows that EZH2 inhibition causes PRC2 redistribution and H3K27me3 retention at differentiation-related genes, but not all cell lines respond to this treatment.
bioRxiv · Dec 29, 2019 · PreprintGenomics