Author

Chloe C. Ence

California Institute for Biomedical Research

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 1

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Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:mouse· 1

Frequent Co-Authors

Amit SharmaiD· 1 shared Arnab K. ChatterjeeiD· 1 shared Bruno N. MelilloiD· 1 shared Eamon ComeriD· 1 shared Han XieiD· 1 shared Jochen ZolleriD· 1 shared Julien BorreliD· 1 shared L. David SibleyiD· 1 shared

Activity by Year

2024-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperMicrobiology

Amit SharmaORCID

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1 paper

Recent·Most cited

Bicyclic pyrrolidine inhibitors of Toxoplasma gondii phenylalanine t-RNA synthetase with antiparasitic potency in vitro and brain exposure

Chloe C. Ence, Taher Uddin, Julien Borrel, Payal Mittal, Han Xie, Jochen Zoller, Amit Sharma, Eamon Comer, Stuart L. Schreiber, Bruno N. Melillo, L. David Sibley, Arnab K. Chatterjee

This paper describes new bicyclic pyrrolidine inhibitors of Toxoplasma gondii PheRS with improved potency, selectivity, and brain exposure compared to previous azetidine-based inhibitors.

ACS Infectious Diseases · May 14, 2024Peer-reviewedMicrobiology