Trends of Plasmodium falciparum molecular markers associated with resistance to artemisinins and reduced susceptibility to lumefantrine in Mainland Tanzania from 2016 to 2021
Catherine Bakari, Celine Isaack Mandara, Rashid A. Madebe, Misago D. Seth, Billy Ngasala, Erasmus Kamugisha, Maimuna Ahmed, Filbert T. Francis, Samwel Bushukatale, Mercy Grace Chiduo, Twilumba Makene, Abdunoor M. Kabanywanyi, Muhidin Kassim Mahende, Reginald Adolph Kavishe, Florida Joseph Muro, , Deus S. Ishengoma
The paper analyzes trends of molecular markers of artemisinin resistance and lumefantrine susceptibility in Plasmodium falciparum from 2016 to 2021 in Tanzania, finding an increase in Y184F mutations and NFD haplotypes.
bioRxiv · Jan 18, 2024 · PreprintMolecular Biology