Billy Ngasala

The paper analyzes genetic diversity of the malaria parasite antigen MSP2 in Sub-Saharan Africa using PCR and long-read sequencing, revealing extensive sequence variation and regional prevalence patterns.

This study examines IgG responses to Plasmodium falciparum MSP2, finding that naturally acquired antibodies do not target conserved termini but instead recognize variable regions and linear epitopes.

This study performs population genomic analysis of Plasmodium ovale species in sub-Saharan Africa, finding differences in nucleotide diversity and signatures of selection between the two species.

The paper analyzes trends of molecular markers of artemisinin resistance and lumefantrine susceptibility in Plasmodium falciparum from 2016 to 2021 in Tanzania, finding an increase in Y184F mutations and NFD haplotypes.

The paper introduces a genomic platform using long-read sequencing to monitor pathogen diversity and identify vaccine antigens in multiclonal infections.

The paper analyzes genetic diversity and drug resistance mutations in Tanzanian Plasmodium falciparum isolates using molecular inversion probes, revealing population structure and geographic patterns of genetic relatedness.

The paper uses whole-genome sequencing to show that Plasmodium falciparum parasites in Zanzibar and mainland Tanzania share genetic ancestry, indicating ongoing importation despite malaria control efforts.

The paper identifies DUP4, a structural variant associated with reduced malaria risk and higher hemoglobin levels in a Tanzanian population.