Özkan Aydemir

The paper identifies tri-SNP haplotypes in HLA-DRA associated with type 1 diabetes and celiac disease, and links them to differences in complement system genes C4A and C4B.

The paper examines changes in chromosome conformation, nuclear organization, and transcription during motor neuron maturation in control and ALS C9orf72 mutant cells, finding delayed maturation in disease models.

This study performs population genomic analysis of Plasmodium ovale species in sub-Saharan Africa, finding differences in nucleotide diversity and signatures of selection between the two species.

The paper introduces two methods to directly estimate malaria parasite complexity of infection from allele frequency data, showing comparable accuracy to existing methods and identifying continental differences in COI.

The paper analyzes genetic diversity and drug resistance mutations in Tanzanian Plasmodium falciparum isolates using molecular inversion probes, revealing population structure and geographic patterns of genetic relatedness.

The paper develops a method to sequence microhaplotypes from Plasmodium falciparum heterozygomes, achieving high coverage, specificity, and sensitivity for detecting polyclonal infections.

The paper analyzes EBV genomes from eBL patients and controls in Kenya, finding type 1 EBV is more common in patients and identifying genetic variants associated with eBL.

This study analyzes the genetic structure of Plasmodium falciparum in the DRC, identifying an east-west haplotype divide linked to antimalarial resistance and evidence of gene flow and selection pressures.

The paper uses whole-genome sequencing to show that Plasmodium falciparum parasites in Zanzibar and mainland Tanzania share genetic ancestry, indicating ongoing importation despite malaria control efforts.