A dicer-related helicase opposes the age-related pathology from SKN-1 activation in ASI neurons
Chris D. Turner, Nicole L. Stuhr, Carmen M. Ramos, Bennett T Van Camp, Sean P. Curran
The paper identifies drh-1 as a mechanism to counteract excessive SKN-1 transcriptional activity in C. elegans, improving healthspan by opposing age-related pathology.
Proceedings of the National Academy of Sciences · Dec 19, 2023Peer-reviewedGenetics