IP6 and PF74 affect HIV-1 Capsid Stability through Modulation of Hexamer-Hexamer Tilt Angle Preference
Chris M. Garza, Matthew Holcomb, Diogo Santos-Martins, Bruce E. Torbett, Stefano Forli
This study uses atomistic simulations to show how IP6 and PF74 modulate HIV-1 capsid stability by altering hexamer-hexamer tilt angles, revealing distinct effects on structural flexibility.
bioRxiv · Mar 11, 2024Biophysics