Interactions among Merlin, Arkadia, and SKOR2 mediate NF2-associated Schwann cell proliferation in human.
Pei-Ciao Tang, Se Young Um, Anderson B. Mayfield, Olena R. Bracho, Christian Del Castillo, Christine Thuyvan Dinh, Derek M. Dykxhoorn, Xue Zhong Liu
The paper investigates Merlin's role in NF2-associated Schwann cell proliferation using a hiPSC model and identifies new interaction partners, Arkadia and SKOR2, that mediate SMAD-dependent TGFβ signaling.
Stem Cell Research & Therapy · Apr 5, 2025Peer-reviewedCell Biology