Author

Christian L Althaus

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 1 Systems Biology· 1

Signature Assays, Organisms & Methods

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Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Approach:statistical model· 1

Frequent Co-Authors

Alan S Perelson· 1 shared Beda Joos· 1 shared Huldrych F Günthard· 1 shared Lucy J Hathaway· 1 shared Magnus UnemoiD· 1 shared Nicola Low· 1 shared Sunniva Foerster· 1 shared

Activity by Year

2014-2015 · peak 1/yr

Co-Author Collaboration Network

7 top collaborators · 9 mutual co-author links

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1 shared paperSystems Biology

Alan S Perelson

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2 papers

Recent·Most cited

Time-kill curve analysis and pharmacodynamic functions for in vitro evaluation of antimicrobials against Neisseria gonorrhoeae

Sunniva Foerster, Magnus Unemo, Lucy J Hathaway, Nicola Low, Christian L Althaus

This study develops a standardized in vitro time-kill curve assay to evaluate antimicrobial activity against Neisseria gonorrhoeae, finding that pharmacodynamic functions reveal varying bactericidal and bacteriostatic effects across antimicrobials.

bioRxiv · Oct 6, 2015Microbiology

Quantifying the turnover of transcriptional subclasses of HIV-1-infected cells

Christian L Althaus, Beda Joos, Alan S Perelson, Huldrych F Günthard

The paper quantifies the turnover of HIV-1-infected cell subclasses using a mathematical model and patient data, finding that latently infected cells rapidly establish during acute infection.

PLoS Computational Biology · Oct 23, 2014Peer-reviewedSystems Biology