Dynamics and spatial genomics of the nascent transcriptome in single mESCs by intron seqFISH
Sheel Shah, Yodai Takei, Wen Zhou, Eric Lubeck, Jina Yun, Chee-Huat Linus Eng, Noushin Koulena, Christopher J. Cronin, Christoph Karp, Eric J. Liaw, Mina Amin, Long Cai
This study uses seqFISH to image nascent transcription active sites in single mouse embryonic stem cells, revealing dynamic spatial distribution and variability in transcription activity.
Cell · Jun 7, 2018Peer-reviewedSystems Biology