Author

Wen Zhou

California Institute of TechnologyORCID 0000-0003-0357-2744Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Systems Biology· 2

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:clustering· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Organism:human· 1 Organism:mouse· 1 Research Focus:spatial domain detection· 1

Frequent Co-Authors

Carsten PetersoniD· 1 shared Chee-Huat Linus Eng· 1 shared Christoph Karp· 1 shared Christopher J. CroniniD· 1 shared Ellen V. RothenbergiD· 1 shared Emil AnderssoniD· 1 shared Eric J. LiawiD· 1 shared Eric LubeckiD· 1 shared

Activity by Year

2018-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperSystems Biology

Carsten PetersonORCID

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2 papers

Recent·Most cited

Multi-scale dynamical modelling of T-cell development from an early thymic progenitor state to lineage commitment

Victor Olariu, Mary A. Yui, Pawel Krupinski, Wen Zhou, Julia Deichmann, Emil Andersson, Ellen V. Rothenberg, Carsten Peterson

The paper develops a multi-scale dynamic model of T-cell development, incorporating gene regulatory networks, epigenetic gates, and proliferation kinetics to simulate commitment dynamics.

Cell Reports · Jan 1, 2021Peer-reviewedSystems Biology

Dynamics and spatial genomics of the nascent transcriptome in single mESCs by intron seqFISH

Sheel Shah, Yodai Takei, Wen Zhou, Eric Lubeck, Jina Yun, Chee-Huat Linus Eng, Noushin Koulena, Christopher J. Cronin, Christoph Karp, Eric J. Liaw, Mina Amin, Long Cai

This study uses seqFISH to image nascent transcription active sites in single mouse embryonic stem cells, revealing dynamic spatial distribution and variability in transcription activity.

Cell · Jun 7, 2018Peer-reviewedSystems Biology