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Christopher C Kyriazis

Department of Ecology and Evolutionary Biology, University of California , Los Angeles, CA 90095-1606 ,

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Aina Martinez i ZuritaiD· 1 shared Kirk E LohmuelleriD· 1 shared

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Evolutionary BiologybioRxivFeb 7, 2024

The impact of non-neutral synonymous mutations when inferring selection on non-synonymous mutations

Aina Martinez i Zurita, Christopher C Kyriazis, Kirk E Lohmueller

This study shows that selection on synonymous mutations can bias inferences of the DFE for nonsynonymous mutations when using demographic parameters estimated from synonymous variants.

DOI 10.1093/genetics/iyaf200

statistical model

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