Aina Zurita Martinez

This study shows that selection on synonymous mutations can bias inferences of the DFE for nonsynonymous mutations when using demographic parameters estimated from synonymous variants.

The paper identifies ergosterol depletion in Nakaseomyces glabratus as a mechanism for amphotericin B resistance without fitness or virulence defects.

PhylogicNDT statistically reconstructs cancer driver timing, subclonal phylogenies, and population dynamics from single- or multi-timepoint sequencing, revealing subtype-specific trajectories and therapy resistance evolution across 498 lung adenocarcinomas.