Author

Christopher R Gignoux

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Genetics· 2

Signature Assays, Organisms & Methods

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Organism:human· 3 Approach:statistical model· 3 Assay:DNA methylation· 2 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Research Focus:genome assembly· 1 Research Focus:GWAS / association mapping· 1 Assay:GWAS summary statistics· 1

Frequent Co-Authors

Celeste Eng· 2 shared Joshua M Galanter· 2 shared Noah ZaitleniD· 2 shared Carlos D Bustamante· 1 shared Chun J Ye· 1 shared Danny Park· 1 shared Dara Torgerson· 1 shared Denise SerebriskyiD· 1 shared

Activity by Year

2016-2017 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 23 mutual co-author links

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2 shared papersGenetics

Celeste Eng

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Author profile →

3 papers

Recent·Most cited

An Ancestry Based Approach for Detecting Interactions

Danny Park, Itamar Eskin, Eun Yong Kang, Eric R Gamazon, Celeste Eng, Christopher R Gignoux, Joshua M Galanter, Esteban Burchard, Chun J Ye, Hugues Aschard, Eleazar Eskin, Eran Halperin, Noah Zaitlen

This paper develops a statistical method using genetic ancestry to detect gene-gene and gene-environment interactions in admixed populations, identifying significant interactions in methylation data.

Genetic Epidemiology · Nov 8, 2017Peer-reviewedGenetics

Differential methylation between ethnic sub-groups reflects the effect of genetic ancestry and environmental exposures

Joshua M Galanter, Christopher R Gignoux, Sam S Oh, Dara Torgerson, Maria Pino-Yanes, Neeta Thakur, Celeste Eng, Donglei Hu, Scott Huntsmann, Harold J Farber, Pedro Avila, Emerita Brigino-Buenaventura, Michael LeNoir, Kelly Meade, Denise Serebrisky, , Noah Zaitlen

This study examines how ethnic self-identification and genetic ancestry influence DNA methylation patterns in individuals of Hispanic descent, finding that ancestry explains much of the variation, but environmental factors also play a significant role.

bioRxiv · Jul 29, 2016Genetics

The Great Migration and African-American genomic diversity

Soheil Baharian, Maxime Barakatt, Christopher R Gignoux, Suyash Shringarpure, Jacob Errington, William J Blot, Carlos D Bustamante, Eimear E Kenny, Scott M Williams, Melinda C Aldrich, Simon Gravel

This study assesses African-American genomic diversity using cohort data, revealing higher African ancestry in the South and migration patterns linked to the Great Migration.

PLOS Genetics · May 27, 2016Peer-reviewed