Carlos D Bustamante

This study assesses African-American genomic diversity using cohort data, revealing higher African ancestry in the South and migration patterns linked to the Great Migration.

This study analyzes recombination rate variation across great apes using genome-wide data, finding PRDM9's role in recombination and rapid hotspot turnover.

The paper presents a framework integrating whole genome sequencing and wearable sensor data into electronic medical records to enhance precision health through personalized monitoring and genomic curation.

This study combines structural models of myosin, exome sequencing, and phenotypic data to identify disease-associated variants in specific structural regions of β-cardiac myosin linked to HCM severity.

GBStools improves genotype accuracy in reduced representation sequencing by correcting restriction site polymorphism errors, showing better performance than standard filters in simulated and empirical human data.

The paper examines how distance from Sub-Saharan Africa correlates with mutational load in diverse human populations, finding that populations further from Africa have higher mutation loads due to recessive mutations.

This study compares two whole genome capture methods on ancient DNA libraries, finding that bait length affects enrichment and that WGC may bias against shorter molecules in single-stranded protocols.