Initiation of human cytomegalovirus secondary envelopment requires the gM/gN glycoprotein complex and involves palmitoylation.
Laura Cortez Rayas, Ronja Rogg, Maximilian Voll, Christopher Thompson, Diana Lieber, Clarissa Read, Jens von Einem
This study identifies the gM/gN glycoprotein complex and palmitoylation as essential for initiating secondary envelopment of HCMV capsids, revealing their role in spatially organizing viral assembly within the cVAC.
Journal of Virology · Dec 8, 2025Peer-reviewedMicrobiology