Genome-scale enzymatic reaction prediction by variational graph autoencoders
Cheng Wang, Chuang Yuan, Yahui Wang, Ranran Chen, Yuying Shi, Gary J. Patti, Qingzhen Hou
The paper introduces MPI-VGAE, a framework for predicting metabolite-protein interactions across organisms, showing improved performance in reconstructing metabolic pathways and disease-specific networks.
bioRxiv · Mar 8, 2023 · PreprintBioinformatics