A multiple-causal-gene-cluster model underlying GWAS signals of Alzheimer's disease
Min Xu, Qianjin Liu, Rui Bi, Yu Li, Chunhua Zeng, Zhongjiang Yan, Quanzhen Zheng, Xiao Li, Chunli Sun, Maosen Ye, Xiong‐Jian Luo, Ming Li, Dengfeng Zhang, Yong‐Gang Yao
The paper identifies multiple causal genes and variants within GWAS loci for Alzheimer's disease and proposes a model where co-dysregulation of gene clusters contributes to disease development.
bioRxiv · May 14, 2021 · PreprintGenetics