Xiao Li

The paper profiles histone lysine crotonylation and lactylation dynamics during neural development and identifies HDAC1-3 as novel erasers of H3K18la.

The paper identifies multiple causal genes and variants within GWAS loci for Alzheimer's disease and proposes a model where co-dysregulation of gene clusters contributes to disease development.

The paper presents a large ASE resource from GTEx v8 with 431 million SNP-level and 153 million haplotype-level measurements, and extends phASER to estimate cis regulatory variant effect sizes.

GTEx v8 maps expression and splicing QTLs in 49 tissues from 838 donors: cis-eQTLs cover 94.7% of protein-coding genes, and cross-tissue QTL sharing mirrors cell-type composition.