Author

Chunna Fan

BGI Group (China)

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Genetics· 1 Genomics· 1

Signature Assays, Organisms & Methods

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Organism:human· 2 Approach:statistical model· 2 Research Focus:variant calling· 2 Assay:whole-genome sequencing· 2

Frequent Co-Authors

Fengxia LiuiD· 2 shared Lijie SongiD· 2 shared Xiaodan WangiD· 2 shared Yan SuniD· 2 shared Yaoshen WangiD· 2 shared Zhiyu PengiD· 2 shared Zhonghai Fang· 2 shared Chaonan ShiiD· 1 shared

Activity by Year

2020-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 43 mutual co-author links

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2 shared papersGenomics

Fengxia LiuORCID

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2 papers

Recent·Most cited

Characterizing sensitivity and coverage of clinical WGS as a diagnostic test for genetic disorders

Yan Sun, Fengxia Liu, Chunna Fan, Yaoshen Wang, Lijie Song, Zhonghai Fang, Rui Han, Zhonghua Wang, Xiaodan Wang, Ziying Yang, Zhenpeng Xu, Jiguang Peng, Chaonan Shi, Hongyun Zhang, Wei Dong, , Zhiyu Peng

This study evaluates the sensitivity and coverage of clinical whole-genome sequencing (WGS) for detecting genetic variants, finding that 40X mean depth achieves high sensitivity for SNVs and indels but not 100%.

BMC Medical Genomics · Apr 13, 2021Peer-reviewedGenomics

Performance characterization of PCR-free whole genome sequencing for clinical diagnosis

Ningzhi Zhang, Meizhen Zhou, Fanwei Zeng, Xiaodan Wang, Fengxia Liu, Zhihong Qiao, Chunna Fan, Yaoshen Wang, Zhonghai Fang, Wentao Dai, Jiale Xiang, Jun Sun, Zhiyu Peng, Lijie Song, Yan Sun

This study evaluates PCR-free whole genome sequencing for clinical diagnosis, showing improved sensitivity and PPV for variant detection compared to PCR-based methods.

bioRxiv · Jun 19, 2020 · PreprintGenetics