Chaonan Shi

This study identifies plant host factors involved in geminiviral DNA replication using proximity labeling and functional assays, revealing the selective repurposing of eukaryotic replication machinery.

This study shows that geminivirus TYLCV uses alternative splicing to generate Rep isoforms with distinct functions in viral replication and gene regulation.

The paper identifies widespread RNA splicing in a plant DNA virus, showing it enhances viral infectivity by expanding the proteome.

This study evaluates the sensitivity and coverage of clinical whole-genome sequencing (WGS) for detecting genetic variants, finding that 40X mean depth achieves high sensitivity for SNVs and indels but not 100%.