Genome Profiling for Aflatoxin B1 Resistance in Saccharomyces cerevisiae Reveals a Role for the CSM2/SHU Complex in Tolerance of Aflatoxin B1-associated DNA Damage
Nick St. John, Julian Freedland, Henri Baldino, Francis Doyle, Cinzia Cera, Thomas J. Begley, Michael Fasullo
The paper identifies 85 AFB1-resistant genes in yeast by screening a deletion library and finds that the CSM2/SHU complex is involved in error-free bypass of AFB1-induced DNA adducts.
G3 Genes Genomes Genetics · Sep 29, 2020Peer-reviewedGenomics