Author

Henri Baldino

Pacific Northwest National LaboratoryORCID 0000-0001-7159-3075Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genomics· 1 Microbiology· 1 Synthetic Biology· 1

Signature Assays, Organisms & Methods

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Organism:bacteria (other)· 2 Assay:whole-genome sequencing· 2 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Approach:genetic perturbation / CRISPR· 1 Approach:statistical model· 1 Research Focus:variant calling· 1

Frequent Co-Authors

Joshua R. ElmoreiD· 2 shared Robert G. EgbertiD· 2 shared Ryan M. FrancisiD· 2 shared Adam M. GussiD· 1 shared Andrew Frank· 1 shared Andrew Wilson· 1 shared Bhavya GuptaiD· 1 shared Cinzia Cera· 1 shared

Activity by Year

2020-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersMicrobiology

Joshua R. ElmoreORCID

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Author profile →

3 papers

Recent·Most cited

Reinforced CRISPR interference enables reliable multiplex gene repression in phylogenetically distant bacteria

Joshua R. Elmore, Ritu Shrestha, Andrew Wilson, Elise M. Van Fossen, Andrew Frank, Ryan M. Francis, Henri Baldino, Molly Stephenson, Bhavya Gupta, Jeane Rivera, Robert G. Egbert

This paper develops a CRISPRi platform for multiplex gene repression in diverse bacteria, demonstrating its effectiveness in multiple species.

bioRxiv · Apr 14, 2025 · PreprintMicrobiology

Genome Profiling for Aflatoxin B1 Resistance in Saccharomyces cerevisiae Reveals a Role for the CSM2/SHU Complex in Tolerance of Aflatoxin B1-associated DNA Damage

Nick St. John, Julian Freedland, Henri Baldino, Francis Doyle, Cinzia Cera, Thomas J. Begley, Michael Fasullo

The paper identifies 85 AFB1-resistant genes in yeast by screening a deletion library and finds that the CSM2/SHU complex is involved in error-free bypass of AFB1-induced DNA adducts.

G3 Genes Genomes Genetics · Sep 29, 2020Peer-reviewedGenomics

The SAGE genetic toolkit enables highly efficient, iterative site-specific genome engineering in bacteria

Joshua R. Elmore, Gara N. Dexter, Ryan M. Francis, Lauren A. Riley, Jay D. Huenemann, Henri Baldino, Adam M. Guss, Robert G. Egbert

The paper introduces SAGE, a genome engineering system for bacteria that enables efficient, iterative integration of DNA constructs without requiring selection.

bioRxiv · Jun 28, 2020 · PreprintSynthetic Biology