Author

Clémence Fournié

Centre National de la Recherche Scientifique

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Systems Biology· 1

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Approach:optimal transport· 1 Assay:scRNA-seq· 1 Approach:statistical model· 1 Research Focus:trajectory inference· 1

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Aymeric BaradatiD· 1 shared Elias VentreiD· 1 shared Fabien Crauste AiD· 1 shared Olivier GandrilloniD· 1 shared Ulysse HerbachiD· 1 shared

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2026-2026 · peak 1/yr

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Aymeric BaradatORCID

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Systems Biologynpj Systems Biology and ApplicationsPeer-reviewedMay 21, 2026

Cell Trajectory Inference based on Optimal Transport and a mechanistic stochastic gene expression model

Clémence Fournié, Elias Ventre, Ulysse Herbach…·Fabien Crauste A

This paper introduces a method for cell trajectory inference using optimal transport with a mechanistic stochastic gene expression model, showing the Bursty model better captures gene dynamics than the Diffusive model.

DOI 10.1038/s41540-026-00743-x

scRNA-seqoptimal transport

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