Author

Clara Lettl

Ottawa Institute of Systems Biology

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

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Genomics· 1 Synthetic Biology· 1

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Approach:statistical model· 2 Research Focus:differential expression· 1 Research Focus:protein design· 1 Assay:protein sequence· 1 Organism:virus· 1 Organism:yeast· 1

Frequent Co-Authors

Bahram SamanfariD· 2 shared Daniel. J. Burnside· 2 shared Duale AhmediD· 2 shared Houman MoteshareieiD· 2 shared Katayoun Omidi· 2 shared Maryam HajikarimlouiD· 2 shared Mohan BabuiD· 2 shared Thomas David Daniel KazmirchukiD· 2 shared

Activity by Year

2017-2018 · peak 1/yr

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10 top collaborators · 44 mutual co-author links

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2 shared papersGenomics

Bahram SamanfarORCID

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2 papers

Recent·Most cited

Heavy metal sensitivities of gene deletion strains for ITT1 and RPS1A connect their activities to the expression of URE2, a key gene involved in metal detoxification in yeast

Houman Moteshareie, Maryam Hajikarimlou, Alex Mulet Indrayanti, Daniel. J. Burnside, Ana Paula Dias, Clara Lettl, Duale Ahmed, Katayoun Omidi, Thomas David Daniel Kazmirchuk, Nathalie Puchacz, Narges Zare, Sarah Takallou, Thet Naing, Raúl Bonne Hernández, William Glen Willmore, , Ashkan Golshani

The paper identifies two yeast genes, ITT1 and RPS1A, whose deletion increases heavy metal sensitivity by affecting URE2 mRNA translation.

PLoS ONE · Sep 19, 2018Peer-reviewedGenomics

Designing Anti-Zika Virus Peptides Derived from Predicted Human-Zika Virus Protein-Protein Interactions

Thomas David Daniel Kazmirchuk, Kevin Dick, Daniel. J. Burnside, Brad Barnes, Houman Moteshareie, Maryam Hajikarimlou, Katayoun Omidi, Duale Ahmed, Andrew Low, Clara Lettl, Mohsen Hooshyar, Andrew Schoenrock, Sylvain Pitre, Mohan Babu, Edana Cassol, , Ashkan Golshani

This study predicts human-Zika virus protein-protein interactions and designs synthetic peptides to disrupt these interactions as potential anti-Zika virus therapeutics.

Computational Biology and Chemistry · Nov 2, 2017Peer-reviewedSynthetic Biology