Endosomal structure and APP biology are not altered in preclinical cellular models of Down syndrome
Claudia Cannavo, Karen Cleverley, Cheryl Maduro, Paige Mumford, DALE A. MOULDING, Elizabeth Fisher, Frances K. Wiseman
The paper investigates endosomal structure and APP biology in Down syndrome mouse models and finds no alterations in endosome number, size, or APP processing.
bioRxiv · Dec 30, 2021 · PreprintNeuroscience