Cortical pyramidal tract neurons constrain pathological dopaminergic motor responses
Mihai Atudorei, Gustaf Erik David Olsson, Christian del Agua Villa, Claudiu Corcea, Ulrik Gether, Maria Angela Cenci, Hartwig Siebner, Mattias Rickhag
This study shows that activating pyramidal tract neurons in the motor cortex reduces pathological dopaminergic motor responses in mice with Parkinson's-like symptoms.
bioRxiv · Oct 28, 2026 · PreprintNeuroscience