Cancer BiologyNature CancerPeer-reviewed
Single cell dissection of developmental origins and transcriptional heterogeneity in B-cell acute lymphoblastic leukemia
Ilaria Iacobucci, Andy G.X. Zeng, Qingsong Gao…·Charles Grenfell Mullighan
This study uses scRNA-seq to analyze B-ALL samples, revealing transcriptional heterogeneity and developmental origins, with specific subtypes associated with distinct cell populations and clinical outcomes.