Temperature-dependent changes in neuronal dynamics in a patient with an SCN1A mutation and hyperthermia induced seizures
Colin Peters, Richard E Rosch, Elaine Hughes, Peter C Ruben
The paper evaluates a temperature-sensitive SCN1A mutation in a patient with Dravet syndrome, showing temperature-dependent channel dysfunction and its impact on neuronal dynamics through computational modeling.
bioRxiv · Apr 13, 2016Neuroscience