Author

Colleen Byrnes

National Institutes of Health

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1

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Research Focus:cell type annotation· 1 Approach:genetic perturbation / CRISPR· 1 Organism:human· 1 Assay:proteomics· 1

Frequent Co-Authors

Benjamin A. Clarke· 1 shared Hongling ZhuiD· 1 shared Mari KonoiD· 1 shared Richard L. ProiaiD· 1 shared Saurav MajumderiD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

5 top collaborators · 10 mutual co-author links

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1 shared paperBiochemistry

Benjamin A. Clarke

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1 paper

Recent·Most cited

1-Deoxysphingolipids Require Very-Long-Chain Ceramide Synthesis to Induce ER Stress and Neurotoxicity

Colleen Byrnes, Benjamin A. Clarke, Hongling Zhu, Saurav Majumder, Mari Kono, Richard L. Proia

This study identifies a pathway involving very-long-chain ceramide synthesis that is essential for 1-deoxysphinganine-induced ER stress and neurotoxicity in SH-SY5Y cells.

bioRxiv · Dec 8, 2025 · PreprintBiochemistry