AAV-mediated gene therapy produces fertile offspring in the Lhcgr-deficient mouse model of Leydig cell failure
Kai Xia, Fulin Wang, Xingqiang Lai, Lin Dong, Peng Luo, Suyuan Zhang, Cuifeng Yang, Hong Chen, Yuanchen Ma, Weijun Huang, Wangsheng Ou, Yuyan Li, Xin Gang Feng, Bin Yang, Congyuan Liu, , Andy Peng Xiang
This study shows that AAV-mediated gene therapy can restore testosterone production and fertility in a mouse model of Leydig cell failure.
Cell Reports Medicine · Oct 20, 2022Peer-reviewedDevelopmental Biology