Structural and immunological characterization of the H3 influenza hemagglutinin during antigenic drift
Rebeca de Paiva Fróes Rocha, Ilhan Tomris, Charles A. Bowman, Emma Stevens, Jason Kantorow, Corinna M. Plitt, Weiwei Peng, Svearike Oeverdieck, Thales Galdino Andrade, James A. Ferguson, Diana D. Jung, Rafael Elias Marques, Sander Herfst, Joost Snijder, Srirupa Chakraborty, , Andrew B. Ward
This study examines how glycan evolution in H3 hemagglutinin affects antigenicity and immunogenicity, showing reduced antibody binding and shifted immune response.
Nature Communications · Dec 11, 2025Peer-reviewedImmunology