Release of BEC-1 from CED-9 stimulates lysosome tubulation in C. elegans by engaging Class III PI3K complex I
Cristian Ricaurte, Aldrich K Wilberg, Joshua P. Gill, Kathryn R. DeLeo, Olga S. Dubuisson, K. Adam Bohnert, Alyssa E. Johnson
This study shows that BEC-1 dissociation from CED-9 in C. elegans promotes lysosomal tubulation and autophagy by activating the Class III PI3K complex I.
bioRxiv · Oct 12, 2026 · PreprintCell Biology