Dosa: A method to covalently barcode proteinsfor high throughput biochemistry
Yashwanth Ashok, Kerry L. Bubb, Curran Oy, Sayeh Gorjifard, Josh T. Cuperus, Christine Queitsch, Stanley Fields
Dosa covalently bars proteins for high-throughput biochemical analysis by linking variants to RNA barcodes via a methyltransferase, enabling assessment of protein function through direct biochemical assays.
Proceedings of the National Academy of Sciences · Jan 2, 2026Peer-reviewedGenomics