A Computational Workflow for Structure-Guided Design of Potent and Selective Kinase Peptide Substrates
Abeeb Abiodun Yekeen, Cynthia J. Meyer, Melissa K. McCoy, Bruce A. Posner, Kenneth D. Westover
This paper introduces Subtimizer, a computational pipeline for designing potent and selective kinase peptide substrates using AI tools, showing improved activity and selectivity in tested kinases.
Journal of Chemical Information and Modeling · Feb 7, 2026Peer-reviewedBioinformatics