Insights for disease modeling from single cell transcriptomics of iPSC-derived Ngn2-induced neurons and astrocytes across differentiation time and co-culture
D Das, Shreyash Sonthalia, G. Stein-O.’Brien, MH. Wahbeh, Kyra L. Feuer, Loyal A. Goff, Carlo Colantuoni, Vasiliki Mahairaki, Dimitrios Avramopoulos
The paper analyzes single-cell transcriptomics data of iPSC-derived neurons and astrocytes to assess their similarity to in vivo counterparts and their disease-related gene expression patterns.
BMC Biology · Apr 2, 2024Peer-reviewedGenetics