Vasiliki Mahairaki

Fast Dynamic Whole-Body In Vivo Cytometry Using Magnetic Particle Imaging

This study uses magnetic particle imaging to dynamically track and quantify therapeutic stem cell accumulation in vivo.

Proteomic identification and validation of novel neuronal EV-based markers for Alzheimers disease biomarker discovery

The paper identifies and validates novel neuronal EV surface markers, CNTNAP2 and STX1B, for Alzheimer's disease biomarker discovery through proteomic analysis of EVs from hiPSC-derived neurons and human brain.

Magnetically Labeled iPSC-Derived Extracellular Vesicles Enable MRI/MPI-Guided Regenerative Therapy for Myocardial Infarction

This study develops magnetically labeled iPSC-derived extracellular vesicles for MRI/MPI-guided myocardial infarction therapy, showing improved cardiac function and detectability.

Multi-Region Brain Organoid: Fusion Organoid with Cerebral, Endothelial and Mid-Hindbrain Components

This paper introduces Multi-Region Brain Organoids (MRBOs) that integrate cerebral, mid/hindbrain, and complex endothelial components, revealing new roles for endothelial cells in brain development.

Insights for disease modeling from single cell transcriptomics of iPSC-derived Ngn2-induced neurons and astrocytes across differentiation time and co-culture

The paper analyzes single-cell transcriptomics data of iPSC-derived neurons and astrocytes to assess their similarity to in vivo counterparts and their disease-related gene expression patterns.

Excitatory neurons derived from human induced Pluripotent Stem Cells show transcriptomic differences in Alzheimers patients from controls

The paper compares transcriptomes of excitatory neurons from Alzheimer's patients and controls, identifying 621 differentially expressed genes and linking them to known Alzheimer's genes and functional networks.

Surface phenotyping and quantitative proteomics reveal differentially enriched proteins of brain-derived extracellular vesicles in Parkinson's disease

The paper identifies differentially enriched proteins in brain-derived extracellular vesicles from Parkinson's disease, PSP, and control samples using surface phenotyping and proteomics.

Astrocyte- and neuron-derived extracellular vesicles from Alzheimer's disease patients effect complement-mediated neurotoxicity

The paper tests whether Alzheimer's disease patient-derived extracellular vesicles induce complement-mediated neurotoxicity in neurons.

Influence of species and processing parameters on recovery and content of brain tissue-derived extracellular vesicles

This study evaluates the impact of species and processing parameters on the recovery and content of brain tissue-derived extracellular vesicles using modified protocols.